Karen Cheng Selected Research

nelotanserin

3/2010

Discovery of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (nelotanserin) and related 5-hydroxytryptamine2A inverse agonists for the treatment of insomnia.

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Karen Cheng Research Topics

Disease

3	Intraabdominal Infections 12/2021 - 01/2019
3	Urinary Tract Infections (Urinary Tract Infection) 12/2021 - 01/2019
2	Healthcare-Associated Pneumonia 12/2021 - 01/2020
2	Ventilator-Associated Pneumonia 12/2021 - 01/2020
2	Pyelonephritis 12/2021 - 01/2020
1	Bacteremia 12/2021
1	Infections 01/2020
1	Headache (Headaches) 01/2020
1	Hematologic Neoplasms (Hematological Malignancy) 01/2020
1	Agammaglobulinemia (Hypogammaglobulinemia) 01/2020
1	Sudden Infant Death (SID) 01/2020
1	Nausea 01/2020
1	Exanthema (Rash) 01/2019
1	Appendicitis 01/2019
1	Pneumonia (Pneumonitis) 01/2019
1	Staphylococcal Infections 01/2019
1	Soft Tissue Infections 01/2019
1	Neutropenia 10/2018
1	Breast Neoplasms (Breast Cancer) 10/2018
1	Neoplasms (Cancer) 10/2018
1	Coronary Artery Disease (Coronary Atherosclerosis) 05/2015
1	Vascular Diseases (Vascular Disease) 05/2015
1	Type 2 Diabetes Mellitus (MODY) 08/2014
1	Heart Diseases (Heart Disease) 08/2014
1	Heart Failure 08/2014
1	Pancreatitis 08/2014
1	Hypoglycemia (Reactive Hypoglycemia) 08/2014
1	Wilms Tumor (Wilm's Tumor) 01/2013
1	Coronary Disease (Coronary Heart Disease) 01/2013
1	Sleep Initiation and Maintenance Disorders (Insomnia) 03/2010

Drug/Important Bio-Agent (IBA)

4	ceftazidime drug combination avibactamIBA 12/2021 - 01/2019
2	Pharmaceutical PreparationsIBA 01/2020 - 01/2019
1	Immunoglobulins (Immunoglobulin)IBA 01/2020
1	Immunoglobulin G (IgG)IBA 01/2020
1	Alanine Transaminase (SGPT)IBA 01/2020
1	Ceftazidime (Fortum)FDA LinkGeneric 01/2020
1	Meropenem (Merrem)FDA LinkGeneric 01/2019
1	Ceftaroline FDA Link 01/2019
1	Metronidazole (Metric)FDA LinkGeneric 01/2019
1	pertuzumabIBA 10/2018
1	Trastuzumab (Herceptin)FDA Link 10/2018
1	Small Interfering RNA (siRNA)IBA 05/2015
1	RNA (Ribonucleic Acid)IBA 05/2015
1	Transcription Factors (Transcription Factor)IBA 05/2015
1	Hypoglycemic Agents (Hypoglycemics)IBA 08/2014
1	Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA 08/2014
1	LinagliptinIBA 08/2014
1	Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA 01/2013
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2013
1	DNA Transposable Elements (Element, IS)IBA 01/2013
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2013
1	nelotanserinIBA 03/2010
1	Urea (Carbamide)FDA LinkGeneric 03/2010

Therapy/Procedure

3	Therapeutics 01/2020 - 08/2014
1	Duration of Therapy 01/2019
1	Drug Therapy (Chemotherapy) 10/2018